Metabolic engineering of mammalian cells has to-date focused primarily
on biopharmaceutical protein production or the manipulation of native
metabolic processes towards therapeutic aims. However, significant
potential exists for expanding these techniques to diverse applications
by looking across the taxonomic tree to bioactive metabolites not
synthesized in animals. Namely, cross-taxa metabolic engineering of
mammalian cells could offer value in applications ranging fromfood and
nutrition to …